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Neuroscience

Violence, mental illness, and the brain — A brief history of psychosurgery: Part 2 — From the limbic system and cingulotomy to deep brain stimulation

Abstract — Knowledge of neuroscience flourished during and in the wake of the era of frontal lobotomy, as a byproduct of psychosurgery in the late 1930s and 1940s, revealing fascinating neural pathways and neurophysiologic mechanisms of the limbic system for the formulation of emotions, memory, and human behavior. The creation of the Klüver‑Bucy syndrome in […]

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Violence, mental illness, and the brain — A brief history of psychosurgery: Part 1 — From trephination to lobotomy

Abstract — Psychosurgery was developed early in human prehistory (trephination) as a need perhaps to alter aberrant behavior and treat mental illness. The “American Crowbar Case” provided an impetus to study the brain and human behavior. The frontal lobe syndrome was avidly studied. Frontal lobotomy was developed in the 1930s for the treatment of mental

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Public health, social science, and the scientific method (Part II)

In Part I, we discussed in general terms some of the shortcomings I encountered in many of the grant proposals submitted during my stint as a grant reviewer for the Centers for Disease Control and Prevention’s National Center for Injury Prevention and Control (NCIPC) in the years 2002-2004.[6] There is no reason to believe that

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Public health, social science, and the scientific method (Part I)

1. Introduction During the years 2002-2004, I served in the Injury Research Grant Review Committee (IRGRC, more recently the “Initial Review Group”) of the Centers for Disease Control and Prevention (CDC) — more specifically, the National Center for Injury Prevention and Control (NCIPC). I participated not only in the major meetings in Atlanta, but also

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