Violence, mental illness, and the brain — A brief history of psychosurgery: Part 1 — From trephination to lobotomy

Abstract — Psychosurgery was developed early in human prehistory (trephination) as a need perhaps to alter aberrant behavior and treat mental illness. The “American Crowbar Case” provided an impetus to study the brain and human behavior. The frontal lobe syndrome was avidly studied. Frontal lobotomy was developed in the 1930s for the treatment of mental […]

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